Publications by authors named "Elliot M Fana"
Article Synopsis
- This study focuses on creating specific primers and a TaqMan probe for the rapid detection and serotyping of the Southern African territory 2 (SAT2) strain of Foot-and-Mouth Disease (FMD).* -
- The new SAT2 RT-qPCR assay showed high performance, with an efficiency of 99% and favorable comparisons to existing methods like ELISA and VP1 sequencing, particularly demonstrating a strong agreement with VP1 sequencing.* -
- Future work is needed to develop similar assays for other serotypes (SAT1 and SAT3) and to collect more field samples to validate the effectiveness of the new SAT2 detection method.*
This report describes the molecular characterization of a serotype O foot-and-mouth disease virus (FMDV) recovered from a field outbreak in the Zambezi region, Namibia during July 2021. Sequence analysis demonstrates that this FMDV belongs to the O/EA-2 topotype sharing closest nucleotide identity (99.5%) to FMD viruses collected since 2018 in Zambia.
View Article and Find Full Text PDFFoot-and-mouth disease (FMD) virus (FMDv), like other ribonucleic acid (RNA) genome viruses, has a tendency to mutate rapidly. As such, available vaccines may not confer enough cross-protection against incursion of new lineages and sublineages. This paper is a retrospective study to determine the topotypes/lineages that caused previous FMD outbreaks in 6 southern African countries and the efficacy of the current vaccines to protect cattle against them.
View Article and Find Full Text PDFArticle Synopsis
- * A study analyzed samples from FMD outbreaks in Zambia from 2015 to 2020, identifying various serotypes and notable changes in the virus's epidemiology, including the introduction of new viral strains in multiple provinces.
- * The findings reveal eight distinct FMD outbreaks, some occurring outside traditionally high-risk areas, emphasizing the need for updated vaccine strategies to effectively manage FMD threats in the region.
Foot-and-mouth disease (FMD) is a highly contagious disease that affects cattle, sheep, goats, pigs, and over 70 species of wildlife. FMD continues to be a major economic concern for livestock productivity in many countries. FMDV has seven serotypes O, A, Asia 1, C, and Southern Africa Territories (SAT) 1, 2, and 3.
View Article and Find Full Text PDFFoot-and-mouth disease (FMD) is considered to be endemic in Ghana. However, our knowledge of the local epidemiology of the disease is restricted by a lack of serological information and data for characterized viruses causing field outbreaks. In order to improve our understanding of the prevailing situation, this study was initiated to establish the FMD viruses (FMDV) circulating in the country.
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