Publications by authors named "Elliot Blue"
Article Synopsis
- The study focuses on establishing Minimal Important Difference (MID) estimates for the FACE-Q Skin Cancer Module, a tool to measure patient outcomes after facial skin cancer surgery.
- Conducted at four U.S. hospitals from April 2020 to April 2022, 990 patients undergoing Mohs Micrographic Surgery provided data through various scales assessing satisfaction and distress at multiple time points.
- The findings indicated specific MID estimates for the scales, which are key for improving the understanding and application of patient-reported outcomes in clinical settings.
Article Synopsis
- Skin cancer is generally treatable, but advanced or spreading cases often have low survival rates and few treatment options.
- Recent advancements in understanding key genes related to skin cancer have led to the development of specific gene expression profiles (GEPs).
- This article reviews diagnostic and prognostic GEPs for squamous cell carcinoma and melanoma to enhance treatment strategies and patient care.
As solid organ transplantation becomes more prevalent, more individuals are living as members of the immunosuppressed population with an elevated risk for cutaneous squamous cell carcinoma (cSCC). Although great progress has been made in understanding the pathogenesis of cSCC in general, little is known about the drivers of tumorigenesis in immunosuppressed patients and organ-transplant recipients, specifically. This systematic review sought to synthesize information regarding the genetic and epigenetic alterations as well as changes in protein and mRNA expression that place this growing population at risk for cSCC, influence treatment response, and promote tumor aggressiveness.
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- - A case study details a 17-year-old female with linear porokeratosis, a skin condition characterized by abnormal keratinization and bone resorption, showing significant improvement with a treatment of 2% cholesterol/2% lovastatin ointment.
- - Porokeratosis involves a skin layer (cornoid lamella) that includes incorrectly matured cells and can arise from mutations in the mevalonate pathway, suggesting a complex genetic basis for the disorder.
- - This is one of the few cases documenting bone resorption related to linear porokeratosis, with only one previous case reported involving a distal digit.
Due to their capacity to self-renew, proliferate and generate multi-lineage cells, adult-derived stem cells offer great potential in regenerative therapies to treat maladies such as diabetes, cardiac disease, neurological disorders and orthopedic injuries. Commonly derived from adipose tissue, the stromal vascular fraction (SVF), a heterogeneous cell population enriched with mesenchymal stem cells (MSCs), has garnered interest as a cellular therapy due to ease of accessibility as an autologous, point-of-care application. However, the heterogeneous cell population within SVF is not historically taken into consideration when injecting into patients.
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