[Toxic shock syndrome consecutive to the presence of vaginal tampon for menstruation regressive after early haemodynamic optimization and activated protein C infusion].

A 19-year-old woman was admitted in the intensive care unit for a septic shock recognized as a menstrual toxic shock syndrome with a Staphylococcus aureus. An early goal oriented therapy was started in order to correct in particular the venous central O(2) saturation (ScvO(2)) associated to an early empiric anti-infectious treatment. A multi-organ failure appeared in a second time, so that we began a protein C activated infusion.

Mouse mast cell sensitization with human IgG and allergen.

The heterologous binding of human IgG to mouse peritoneal mast cells was studied in vitro. The specific percentage of mast cell degranulation after treatment with sera heated for 2 hours at 57 degrees C was determined. These sera were obtained from normal or allergic patients, skin test positive to grass mix or dust, and then challenged separately with each allergen.