Publications by authors named "Ellie Jung Hwa Yoo"
Intercluster reactions show that (CH3)2S(+)CH2CO2H is a better methyl cation donor than (CH3)3N(+)CH2CO2H.
Eur J Mass Spectrom (Chichester)
August 2011
Article Synopsis
- The study investigates the methylating properties of two zwitterionic agents, dimethylsulfonioacetate (DMSA) and glycine betaine (GB), through gas-phase experiments involving collision-induced dissociation (CID) of their dimers containing arginine.
- The results indicate that protonated DMSA is a more effective methylating agent compared to protonated GB, as evidenced by consistent yields of methyl cation transfer products.
- Further analysis shows that methylation occurs in a specific form of arginine when complexed with DMSA, and theoretical calculations support that the methylation process with DMSA is favored over GB both kinetically and thermodynamically.
Electrospray ionization and tandem mass spectrometry experiments have been used to study the fragmentation and electron-ion interactions of doubly charged zwitterionic clusters, [M(15) + 2H](2+) (where M = Glycine Betaine (GB), (CH(3))(3)N(+)CH(2)CO(2)(-), and Dimethylsulfonioacetate (DMSA), (CH(3))(2)S(+)CH(2)CO(2)(-)) which are close to the stability limit, i.e., the Coulomb repulsion of the charge within the cluster competes with attractive forces.
View Article and Find Full Text PDFThe fixed charge zwitterionic sulfur betaines dimethylsulfonioacetate (DMSA) (CH(3))(2)S(+)CH(2)CO(2)(-) and dimethylsulfoniopropionate (DMSP) (CH(3))(2)S(+)(CH(2))(2)CO(2)(-) have been synthesized and the structures of their protonated salts (CH(3))(2)S(+)CH(2)CO(2)H···Cl(-) [DMSA.HCl] and (CH(3))(2)S(+)(CH(2))(2)CO(2)H···Pcr(-) [DMSP.HPcr] (where Pcr = picrate) have been characterized using X-ray crystallography.
View Article and Find Full Text PDF