Publications by authors named "Ellie Gauthier"
Article Synopsis
- * In a review of clinical trials, only two out of five showed significant changes in gut microbiota from NNSs like saccharin and sucralose, with these sweeteners possibly worsening glycemic tolerance.
- * Evidence from three out of four cross-sectional studies suggested a link between NNSs and gut microbiota composition, while clinical trials on polyols showed positive prebiotic effects, yet these studies had limitations that compromise their reliability.
Article Synopsis
- A genetic risk score (GRS) developed in the FAS Study was tested for its ability to predict how plasma triglycerides (TG) respond to omega-3 fatty acid supplementation.
- Recent findings from the UK Biobank identified new SNPs linked to plasma lipid levels, which were added to the original GRS in the hopes of improving prediction accuracy.
- However, after testing these modified GRSs (GRS32, GRS38, GRS46), the original GRS31 still demonstrated the best predictive capability for TG responses, indicating that adding new SNPs didn't enhance its effectiveness.
There is a significant lack of consistency used to determine the scientific validity of nutrigenetic research. The aims of this study were to examine existing frameworks used for determining scientific validity in nutrition and/or genetics and to determine which framework would be most appropriate to evaluate scientific validity in nutrigenetics in the future. A systematic review (PROSPERO registration: CRD42021261948) was conducted up until July 2021 using Medline, Embase, and Web of Science, with articles screened in duplicate.
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