Publications by authors named "Ellen Combs"
Introduction: Appalachian populations have some of the highest rates of overdose and comorbidity, all of which are considered risk factors for and contributors to chronic pain.
Purpose: The purpose of this study was to examine the associations of comorbidity, disability (physical limitations), and depression with chronic pain among a community-based sample of Appalachian adults living with diabetes.
Methods: This study used baseline data to conduct a secondary analysis of cross-sectional data (n=356).
Article Synopsis
- Type 2 diabetes mellitus (T2DM) in Appalachia is linked to high rates of depression, but limited research exists on this relationship in the region despite the prevalence of both conditions.
- The study focused on adults in Appalachia, Kentucky, analyzing data to explore associations between T2DM and depressive symptoms, using various demographic and health parameters.
- Results showed that 25% of the 365 participants reported depressive symptoms, with factors like age, comorbid conditions, employment status, gender, and financial status being related to higher rates of depression.
Acalculous cholecystitis is an acute inflammatory disease of the gall bladder with high morbidity and mortality rate. It can be seen in trauma, burns, sepsis, total parenteral nutrition, prolonged fasting, and autoimmune diseases. However, there are very few reports of acalculous cholecystitis with macrophage activation syndrome (MAS) and hemophagocytic lymphohistiocytosis (HLH) in patients with underlying rheumatic/autoimmune disorders.
View Article and Find Full Text PDFBackground: The aim of this study was to examine whether cultural factors, such as religiosity and social support, mediate/moderate the relationship between personal/psychosocial factors and T2DM self-care in a rural Appalachian community.
Methods: Regression models were utilized to assess for mediation and moderation. Multilevel linear mixed effects models and GEE-type logistic regression models were fit for continuous (social support, self-care) and binary (religiosity) outcomes, respectively.