Comparison among adjuvant treatments for primary pterygium: a network meta-analysis.

Purpose: Pterygium is a frequent ocular disease, where the major challenge is the high level of recurrence after its surgical removal. We performed a network meta-analysis to identify, among several adjuvant treatments for primary pterygium, which is the best to prevent recurrence.

Methods: A search was conducted using PubMed, Scientific Electronic Library Online, Latin American and Caribbean Centre on Health Sciences and Cochrane Eyes and Vision Group Trials Register between 1993 and 2015 for randomisedclinical trials (RCTs) comparing adjuvant treatments following primary pterygium surgery.

Dry eye disease treatment: a systematic review of published trials and a critical appraisal of therapeutic strategies.

Dry eye disease (DED) treatment is an area of increasing complexity, with the emergence of several new treatment agents in recent years. Evaluation of the efficacy of these agents is limited by heterogeneity in outcomes definition and the small number of comparative studies. We provide a systematic review of clinical trials (CTs) related to DED treatment and a critical appraisal of CT public databases.

Radiation therapy for Graves' ophthalmopathy: a systematic review and meta-analysis of randomized controlled trials.

Purpose: To evaluate the efficacy of radiotherapy (RT) with total dose of 20 Gy (RT 20 Gy) in the treatment of Graves' ophthalmopathy.

Methods: A systematic review and meta-analysis of randomized controlled trials was performed comparing RT 20 Gy with or without glucocorticoid to clinical treatments for Graves' ophthalmopathy. The MEDLINE, EMBASE, Cochrane Library databases and recent relevant journals were searched.

Conjunctival autograft alone or combined with adjuvant beta-radiation? A randomized clinical trial.

Purpose: To evaluate the effectiveness and safety of postoperative low single-dose of beta-irradiation (β-RT) in pterygium comparing conjunctival autograft (CAG) surgery with CAG plus adjuvant β-RT in a randomized clinical trial.

Methods: This trial was designed as a prospective, randomized, single-center study. Surgery was performed in all cases according to the CAG technique.

Low or high fractionation dose β-radiotherapy for pterygium? A randomized clinical trial.

Purpose: Postoperative adjuvant treatment using β-radiotherapy (RT) is a proven technique for reducing the recurrence of pterygium. A randomized trial was conducted to determine whether a low fractionation dose of 2 Gy within 10 fractions would provide local control similar to that after a high fractionation dose of 5 Gy within 7 fractions for surgically resected pterygium.

Methods: A randomized trial was conducted in 200 patients (216 pterygia) between February 2006 and July 2007.

[Dry eye: etiopathogenesis and treatment].

Dry eye is a multifactorial disease of tears and ocular surface that causes discomfort, visual disturbance and tear film instability. It is a common disorder that affects specially adults and women and can cause quality of life impairment comparable to migraine, shortness of breath and chronic renal insufficiency, depending on its symptoms or complications. New concepts regarding physiopathology, classification and treatment have been presented and should be known by ophthalmologists because of their relevance on day-by-day application.

Whole brain radiotherapy with radiosensitizer for brain metastases.

Purpose: To study the efficacy of whole brain radiotherapy (WBRT) with radiosensitizer in comparison with WBRT alone for patients with brain metastases in terms of overall survival, disease progression, response to treatment and adverse effects of treatment.

Methods: A meta-analysis of randomized controlled trials (RCT) was performed in order to compare WBRT with radiosensitizer for brain metastases and WBRT alone. The MEDLINE, EMBASE, LILACS, and Cochrane Library databases, in addition to Trial registers, bibliographic databases, and recent issues of relevant journals were researched.

[Assessment of visual acuity evaluation performed by teachers of the "Eye in eye" program in Marília-SP, Brazil].

Purpose: To assess quality and cut-off point (VA <0.7) of the examinations performed by teachers to detect reduced visual acuity (VA) in schoolchildren participants of the project called "Eye in eye " in Marilia-SP, Brazil.

Methods: Visual acuity measurements were performed by trained teachers using Snellen's chart.

Long-term results and prognostic factors of fractionated strontium-90 eye applicator for pterygium.

Purpose: To evaluate the long-term safety, effectiveness, and prognostic factors of fractionated postoperative beta-irradiation.

Methods And Materials: Between 1993 and 2005, 623 patients with 737 pterygium lesions were treated with a strontium-90 eye applicator after surgical excision. The median follow-up period was 60 months (range, 6.

[Urbach-Wiethe syndrome: a case report].

We present a case of Urbach-Wiethe syndrome with typical findings, including ocular lesions. A 15-year-old girl was referred to our department complaining of itchy eyelid lesions (moniliform blepharosis) associated with other systemic manifestations. Diagnosis was confirmed by performing skin biopsy.