Publications by authors named "Ella B Martell"
Transplant Cell Ther
February 2024
Article Synopsis
- CAR-T therapy has shown promising results in treating relapsed/refractory multiple myeloma (RRMM), but frequent relapses highlight a need to understand mechanisms of resistance.
- Researchers used advanced flow cytometry to analyze T cell changes in patients at various stages of multiple myeloma, finding distinct T cell phenotypes in RRMM and post-CAR-T relapse cases compared to healthy individuals.
- In RRMM and post-CAR-T relapse patients, T cells exhibited multiple inhibitory markers, suggesting that these markers may play a significant role in the resistance observed after CAR-T therapy.
