Publications by authors named "Elke Conrad"
Thyroid nodules are common yet remain a diagnostic challenge. While ultrasound and Thyroid Imaging Reporting and Data Systems (TIRADS) are accepted as standard, the use of thyroid scintigraphy in euthyroid patients is debated. The European Association of Nuclear Medicine advocates it, whereas the American Thyroid Association and European Thyroid Association do not.
View Article and Find Full Text PDFA 72-year-old woman presented to our emergency centre with acute horizontal diplopia. Neurological examination revealed an isolated abducens nerve paresis on the left. Hilar enlargement seen on the chest x-ray and an elevated serum ACE level led us to suspect sarcoidosis, but the patient declined further evaluation.
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- The enzyme MGMT is crucial for DNA repair by removing harmful methyl groups from DNA, and researchers identified a genetic variation (SNP rs12917) near its active site in Hodgkin lymphoma (HL) cell lines and patients.
- The study analyzed the presence of this SNP in five HL cell lines and 29 pediatric HL patients, examining its correlation with factors like age, gender, and treatment response.
- Findings revealed that the minor T allele was present in some cell lines and patients, with those carrying the C allele showing better metabolic responses to treatment and fewer needing radiation therapy, suggesting that this polymorphism could influence treatment outcomes in pediatric HL.