Publications by authors named "Elizaveta O Mamedova"

Changes in the expression of non-coding ribonucleic acids (ncRNAs) take part in the formation of various tumors. Multiple endocrine neoplasia syndrome type 1 (MEN1) is a rare autosomal dominant disease caused by mutations of the MEN1 gene encoding the menin protein. This syndrome is characterized by the occurrence of parathyroid tumors, gastroenteropancreatic neuroendocrine tumors, pituitary adenomas, as well as other endocrine and non-endocrine tumors.

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Cushing’s syndrome accounts for approximately 20–30% of endogenous hypercortisolism cases, and adrenal involvement can be either unilateral or bilateral. Cushing’s syndrome due to bilateral adrenal tumors is extremely rare. Adrenal oncocytomas are another rare cause of endogenous hypercortisolism: about 13 cases are described in the literature.

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Article Synopsis
  • The registry serves as a key resource for understanding acromegaly patients in the Russian Federation, focusing on their demographics and treatment outcomes.
  • Analysis of a database with 4114 acromegaly patients revealed that 32% achieved full clinical remission, while 68% did not, with some showing improvement but not complete remission.
  • The study also noted an increase in neurosurgical treatments from 2012 to 2019, with remission rates differing based on treatment type (40.47% for surgery vs. 28.95% for medical therapy), highlighting evolving treatment practices in managing the disease.
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