Incorporating Cardiovascular Risk Assessment into Adolescent Reproductive Health and Primary Care Visits.

Study Objective: This study aimed to evaluate the usability and feasibility of incorporating a cardiovascular risk assessment tool into adolescent reproductive health and primary care visits.

Design, Setting, And Participants: We recruited 60 young women ages 13-21 years to complete the HerHeart web-tool in 2 adolescent clinics in Atlanta, GA.

Main Outcome Measures: Participants rated the tool's usability via the Website Analysis and Measurement Inventory (WAMMI, range 0-95) and their perceived 10-year and lifetime risk of cardiovascular disease (CVD) on a visual analog scale (range 0-10).

Assessing and Promoting Cardiovascular Health for Adolescent Women: User-Centered Design Approach.

Background: Cardiovascular disease (CVD) is the leading cause of death among women in the United States. A considerable number of young women already have risk factors for CVD. Awareness of CVD and its risk factors is critical to preventing CVD, yet younger women are less aware of CVD prevalence, its risk factors, and preventative behaviors compared to older women.

Author Correction: A pH-correctable, DNA-based fluorescent reporter for organellar calcium.

The originally published paper has been updated to include the following new reference, added as ref. 18: Albrecht, T., Zhao, Y.

A pH-correctable, DNA-based fluorescent reporter for organellar calcium.

It is extremely challenging to quantitate lumenal Ca in acidic Ca stores of the cell because all Ca indicators are pH sensitive, and Ca transport is coupled to pH in acidic organelles. We have developed a fluorescent DNA-based reporter, CalipHluor, that is targetable to specific organelles. By ratiometrically reporting lumenal pH and Ca simultaneously, CalipHluor functions as a pH-correctable Ca reporter.