Partnering with Students to Develop a Capstone for a Graduate Health Informatics Program.

Objective:  This study aimed to assess the desirability, feasibility, and sustainability of integrating a project-based capstone course with the course-based curriculum of an interdisciplinary MSc Health Informatics program guided by a student-partnered steering committee and student-centered approach.

Methods:  We conducted an online cross-sectional survey ( = 87) and three semistructured focus groups ( = 18) of health informatics students and alumni. Survey data were analyzed descriptively.

Do family dinners reduce the risk for early adolescent substance use? A propensity score analysis.

The risks of early adolescent substance use on health and well-being are well documented. In recent years, several experts have claimed that a simple preventive measure for these behaviors is for families to share evening meals. In this study, we use data from the 1997 National Longitudinal Study of Youth (n = 5,419) to estimate propensity score models designed to match on a set of covariates and predict early adolescent substance use frequency and initiation.

Management of patients with primary central nervous system lymphoma treated with high-dose methotrexate.

Primary central nervous system lymphoma (PCNSL) is a rare, extranodal form of non-Hodgkin lymphoma that most commonly presents with neurologic changes. Comprehensive workup to diagnose PCNSL and rule out nodal non-Hodgkin lymphoma is critical to the development of an appropriate plan for therapy. Past PCNSL treatments have included whole-brain radiation or steroids, but high-dose methotrexate (MTX) has emerged as initial therapy.

Social marketing improved the use of multivitamin and mineral supplements among resource-poor women in Bolivia.

Objective: To test the hypothesis that social marketing improves women's awareness and consumption of multivitamin and mineral supplements.

Design: Formative research and baseline and final surveys using a multistaged stratified cluster sample.

Setting: Department of Santa Cruz, Bolivia.

Phase I study of a MUC1 vaccine composed of different doses of MUC1 peptide with SB-AS2 adjuvant in resected and locally advanced pancreatic cancer.

MUC1 is a glycoprotein overexpressed in tumors as a hypoglycosylated form. A vaccine composed of a 100-amino acid peptide corresponding to five 20-amino acid long repeats, and SB-AS2 adjuvant, was tested in a phase I study for safety, toxicity, and ability to elicit or boost MUC1-specific immune responses. Patients with resected or locally advanced pancreatic cancer without prior chemotherapy or radiotherapy were eligible.