Th1/Th17-mediated Immunity and Protection from Peripheral Neuropathy in Wildtype and IL10 BALB/c Mice Infected with a Guillain-Barré Syndrome-associated Strain.

is an important cause of bacterial gastroenteritis worldwide and is linked to Guillain-Barré syndrome (GBS), a debilitating postinfectious polyneuropathy. The immunopathogenesis of GBS involves the generation of antibodies that are cross reactive to lipooligosaccharide and structurally similar peripheral nerve gangliosides. Both the infecting strain and host factors contribute to GBS development.