Publications by authors named "Elizabeth Tschanz"
Introduction: The burn comb model is a well-established model for studying secondary burn progression. It creates four rectangular burn surfaces intercalated by three unburned zones prone to secondary burn progression. While burn progression is a tri-dimensional phenomenon, of which the vertical extension from the superficial to deeper tissue layer is clinically most relevant, the models initial focus was mainly on the horizontal surface extension within interspaces.
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- Buruli ulcer (BU) is an infectious skin disease, and this study investigates its key histopathological features using 4-mm skin punch biopsies in Cameroon from 2011 to 2013.
- The study involved 364 patients with 422 lesions, identifying that out of 99 ulcerated lesions diagnosed as BU, histological analysis confirmed BU in 32, showing specific necrotic patterns and bacterial presence.
- The findings emphasize that punch biopsies are crucial for accurately diagnosing BU and differentiating it from other chronic ulcers, primarily characterized by subcutaneous necrosis and the detection of acid-fast bacilli.
Do 40% of patients resected for barrett esophagus with high-grade dysplasia have unsuspected adenocarcinoma?
Arch Pathol Lab Med
February 2005
Results of studies conducted in the last 2 decades suggest that the detection of high-grade dysplasia in patients with Barrett esophagus is the harbinger of a synchronous adenocarcinoma, which remains undetected even by rigorous biopsy protocols but is discovered during resection of the esophagus. The reported prevalence of synchronous carcinomas ranges from 0% to 75%. Other researchers maintain that appropriate surveillance programs can be used to detect carcinomas at a curable stage and to prevent unnecessary esophagectomies.
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