Publications by authors named "Elizabeth Telford"
Article Synopsis
- Logged and disturbed forests, often seen as degraded, actually harbor significant biodiversity and should not be dismissed in conservation efforts.
- A study in Sabah, Malaysia examined the effects of logging intensity on 1,681 species, revealing two important conservation thresholds.
- Lightly logged forests (less than 29% biomass removed) can recover well, while heavily degraded forests (over 68% biomass removed) may need more intensive recovery efforts, highlighting the varying conservation values of logged forests.
Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries.
Mol Ther Methods Clin Dev
June 2020
Generation and screening of libraries of adeno-associated virus (AAV) variants have emerged as a powerful method for identifying novel capsids for gene therapy applications. For the majority of libraries, vast population diversity requires multiplexed production, in which a library of inverted terminal repeat (ITR)-containing plasmid variants is transfected together into cells to generate the viral library. This process has the potential to be confounded by cross-packaging and mosaicism, in which particles are comprised of genomes and capsid monomers derived from different library members.
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