Publications by authors named "Elizabeth T Paz-Pacheco"

Article Synopsis
  • - Type 2 diabetes mellitus (T2DM) significantly impacts the quality of life for many Filipinos, with genetic factors contributing to 30-70% of the disease risk.
  • - This study examined the genetic variants linked to T2DM among Filipinos by comparing 66 individuals with diabetes to 121 without, identifying nine significant genetic variants tied to glucose and energy metabolism.
  • - Key variants, particularly CDKAL1 (rs7766070), show the highest risk levels, suggesting their potential use as markers for early detection and prevention of T2DM in the Filipino population.
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Background: Coronary artery disease (CAD) is a common complication of Type 2 diabetes mellitus (T2DM). Understanding the pathogenesis of this complication is essential in both diagnosis and management. Thus, this study aimed to characterize the presence of CAD in T2DM using molecular markers and pathway analyses.

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