Prognostic value of labs ordered on patients hospitalized with COVID-19.

: Hospitalists at our institution have taken on most non-intensive care unit (ICU) coronavirus disease 2019 (COVID-19) care. Based on sparse research, our institution developed a protocol for ordering labs for this patient population, including routine admission labs in addition to eight COVID-19-specific daily labs. The study goal is to determine if COVID-19-specific admission labs have any prognostic value beyond that provided by routine admission labs and vitals, and costs of labs with no prognostic value.

Association Between Postoperative Delirium and Long-term Cognitive Function After Major Nonemergent Surgery.

Importance: Postoperative delirium is associated with decreases in long-term cognitive function in elderly populations.

Objective: To determine whether postoperative delirium is associated with decreased long-term cognition in a younger, more heterogeneous population.

Design, Setting, And Participants: A prospective cohort study was conducted at a single academic medical center (≥800 beds) in the southeastern United States from September 5, 2017, through January 15, 2018.

Sexual dimorphisms in the associations of BMI and body fat with indices of pubertal development in girls and boys.

Context: The effect of obesity and concomitant insulin resistance on pubertal development is incompletely elucidated.

Objective: To determine how measures of adiposity and insulin resistance are associated with pubertal maturation in boys and girls.

Setting And Design: Breast and pubic hair Tanner stage and testicular volume by orchidometry were determined by physical examination in 1066 children.

Longitudinal study of depressive symptoms and progression of insulin resistance in youth at risk for adult obesity.

OBJECTIVE The purpose of this study was to determine whether having childhood depressive symptoms is a risk factor that prospectively predicts impairment in glucose homeostasis. RESEARCH DESIGN AND METHODS A non-treatment-seeking sample of 115 children (aged 5-13 years), oversampled for being at risk for adult obesity, was assessed at baseline and again ~6 years later. Children self-reported depressive symptoms using the Children's Depression Inventory at baseline.

Acute effects of betahistine hydrochloride on food intake and appetite in obese women: a randomized, placebo-controlled trial.

Background: Central nervous system histaminergic tone is thought to play a role in appetite regulation. In animal models, histamine receptor 1 (HRH1) agonists and histamine receptor 3 (HRH3) antagonists decrease food intake.

Objective: The objective of this study was to examine the acute effects of betahistine hydrochloride (an HRH1 agonist and HRH3 antagonist) on food intakes and appetites.

Correlates of intimate partner violence among female patients at a North Carolina emergency department.

Objective: This paper identifies comorbid factors among female emergency department (ED) patients who have experienced intimate partner violence (IPV).

Methods: 321 adult female patients completed self-administered questionnaires while in an urban North Carolina emergency department. IPV was assessed by questioning whether the patient had ever been afraid of a partner, physically hurt or threatened by a partner, or forced to have sex by a partner.