Publications by authors named "Elizabeth Schiffman"

Objective: Pet ownership among people experiencing homelessness (PEH) is common, but access to shelter, veterinary care, and flea-preventative products for PEH who own pets in the US is not well described. We sought to evaluate current knowledge of fleas and flea-borne diseases and characterize practices around pets and service animals among staff at homeless shelters and outreach organizations.

Methods: In-person surveys were administered to staff at homeless shelters and on outreach teams in 7 states from August 2022 to April 2023 to evaluate knowledge, attitudes, and practices and to assess homeless shelter/organizational characteristics.

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Accurate and timely mortality surveillance is crucial for elucidating risk factors, particularly for emerging diseases. We compared use of COVID-19 keywords on death certificates alone to identify COVID-19 deaths in Minnesota, USA, during 2020-2022, with use of a standardized mortality definition incorporating additional clinical data. For analyses, we used likelihood ratio χ and median 1-way tests.

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Aims And Methods: In the United States, blacklegged Ixodes spp. ticks are the primary vector of Lyme disease. Minnesota is among the states with the highest reported incidence of Lyme disease, having an average of 1857 cases reported annually during 2011-2019.

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Article Synopsis
  • Louse-borne Bartonella quintana and flea-borne murine typhus are serious diseases affecting people experiencing homelessness in the US, but service staff's awareness and prevention knowledge is limited.
  • A survey of 333 staff from 89 shelters across seven states revealed that while most recognize the problem of body lice and fleas, only about half understand their disease transmission potential, and less than 25% can describe proper management protocols.
  • There are significant gaps in understanding among staff regarding these diseases, highlighting the need for training to improve prevention efforts and ensure equitable service access for affected individuals.
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Background: To characterize neurodevelopmental abnormalities in children up to 36 months of age with congenital Zika virus exposure.

Methods: From the U.S.

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Article Synopsis
  • Borrelia miyamotoi, a bacteria spread by Ixodes ticks, was identified as a cause of hard tick relapsing fever in the US in 2013, leading to surveillance efforts in nine states.
  • From 2013 to 2019, 300 cases were reported, with 166 confirmed and a median patient age of 52; most cases were in males and occurred primarily during the summer months.
  • Common symptoms included fever and headache, with 28% experiencing recurring fevers and 13% of patients hospitalized; continued surveillance is essential to better understand this disease's incidence and impact.
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As the primary vector of Lyme disease spirochetes and several other medically significant pathogens, Ixodes scapularis presents a threat to public health in the United States. The incidence of Lyme disease is growing rapidly in upper midwestern states, particularly Michigan, Minnesota, and Wisconsin. The probability of a tick bite, acarological risk, is affected by the phenology of host-seeking I.

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  • Lyme disease and other tick-borne diseases are significant public health concerns in the Upper Midwest, particularly in Michigan, Minnesota, and Wisconsin, prompting officials to recommend various prevention measures.
  • A survey conducted in 2019 across 48 high-risk counties revealed that while 98% of people had heard of Lyme disease and many recognized its seriousness, only about 25% thought tick-borne diseases were common in their community.
  • Despite this, there seems to be a high willingness among the population to adopt preventive behaviors, with 82% willing to perform daily tick checks and over 60% open to using bug repellent and tick control products for pets.*
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  • Traditional surveillance for Lyme disease involves intensive follow-up on positive lab results, which isn't efficient in high-incidence areas and leads to inconsistencies in data.
  • A study analyzed Lyme disease data from 10 states between 2012-2018, revealing that 55% of positive lab results were classified as confirmed or probable cases, while 18% were determined not to be cases at all.
  • Shifting to a laboratory-based surveillance model could standardize reporting and potentially increase reported cases by about 1.2 times, freeing up public health resources for better prevention efforts.
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  • * Among 6,799 live-born infants studied from December 2015 to March 2018, 4.6% had Zika-related birth defects, with a higher rate of 6.1% in those with confirmed infection.
  • * Common defects included microcephaly and other brain abnormalities, with many infants showing multiple defects, highlighting the need for targeted surveillance during potential Zika outbreaks.
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  • Lyme disease cases are rising, prompting the development of new vaccine candidates, but understanding public acceptance is crucial before market release.
  • A survey conducted in June-July 2018 across several states found that 64% of respondents were willing to get vaccinated, while 30% were uncertain, and 7% were unwilling.
  • Factors influencing vaccine hesitancy included being non-White, having less education, safety concerns, low confidence in vaccines, and a low perceived risk of Lyme disease.
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  • Since February 2020, the U.S. has reported about 6.5 million COVID-19 cases and approximately 190,000 deaths, with a focus on individuals under 21 years old.
  • Among the 121 deaths in this age group during the early pandemic, 63% were males, and most were aged between 10-20 years, with a significant percentage being Hispanic and Black.
  • About 75% of those who died had underlying medical conditions, highlighting the need for ongoing monitoring and effective prevention strategies as schools reopen.
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  • Studies show that despite global malaria reduction, cases are increasing in the U.S., particularly among travelers from sub-Saharan Africa, especially VFRs (visiting friends and relatives).
  • The research aimed to identify differences in malaria prevention knowledge, attitudes, and practices between VFRs and other travelers to Africa through a comprehensive survey involving 489 participants.
  • Results indicated that VFRs diagnosed with malaria had more frequent trips to their home country and showed greater concern about malaria risks when they took preventive medications compared to those who did not.
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Most diagnostic testing for West Nile virus (WNV) disease is accomplished using serologic testing, which is subject to cross-reactivity, may require cumbersome confirmatory testing, and may fail to detect infection in specimens collected early in the course of illness. The objective of this project was to determine whether a combination of molecular and serologic testing would increase detection of WNV disease cases in acute serum samples. A total of 380 serum specimens collected ≤7 days after onset of symptoms and submitted to four state public health laboratories for WNV diagnostic testing in 2014 and 2015 were tested.

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Background: The clinical findings among children with postnatally acquired Zika virus disease are not well characterized. We describe and compare clinical signs and symptoms for children aged <18 years.

Methods: Zika virus disease cases were included if they met the national surveillance case definition, had illness onset in 2016 or 2017, resided in a participating state, and were reported to the Centers for Disease Control and Prevention.

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Although immigrants who visit friends and relatives (VFRs) account for most of the travel-acquired malaria cases in the United States, there is limited evidence on community-level risk factors and best practices for prevention appropriate for various VFR groups. Using 2010-2014 malaria case reports, sociodemographic census data, and health services data, we explored and mapped community-level characteristics to understand who is at risk and where imported malaria infections occur in Minnesota. We examined associations with malaria incidence using Poisson and negative binomial regression.

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In the north-central United States, the blacklegged tick (Ixodes scapularis) is currently known to vector seven human pathogens. These include five bacteria (Borrelia burgdorferi sensu stricto, Borrelia mayonii, Borrelia miyamotoi, Anaplasma phagocytophilum, Ehrlichia muris eauclairensis), one protozoan (Babesia microti) and one virus (Powassan). We sought to assess the prevalence and distribution of these pathogens in host-seeking nymphs collected throughout Minnesota, a state on the northwestern edge of the tick's expanding range, where reported cases of I.

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is the vector of at least seven human pathogens in Minnesota, two of which are known to cause Lyme disease ( sensu stricto and ). In Minnesota, the statewide incidence of Lyme disease and other -borne diseases and the geographic extent over which cases have been reported have both increased substantially over the last two decades. These changes correspond with an expanding distribution of over a similar time frame.

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We have previously described a novel taxon of the genus Ehrlichia (type strain WisconsinT), closely related to Ehrlichia muris, that causes human ehrlichiosis among patients with exposures to ticks in the upper midwestern USA. DNA from this bacterium was also detected in Ixodes scapularis and Peromyscus leucopus collected in Minnesota and Wisconsin. To determine the relationship between the E.

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We report on 9 cases of male-to-female sexual transmission of Zika virus in the United States occurring January-April 2016. This report summarizes new information about both timing of exposure and symptoms of sexually transmitted Zika virus disease, and results of semen testing for Zika virus from 2 male travelers.

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Lyme borreliosis (LB) is a multisystem disease caused by spirochetes in the Borrelia burgdorferisensu lato (Bbsl) genospecies complex. We previously described a novel Bbsl genospecies (type strain MN14-1420T) that causes LB among patients with exposures to ticks in the upper midwestern USA. Patients infected with the novel Bbsl genospecies demonstrated higher levels of spirochetemia and somewhat differing clinical symptoms as compared with those infected with other Bbsl genospecies.

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Article Synopsis
  • Lyme borreliosis, primarily caused by the Borrelia burgdorferi sensu lato genospecies, is the most prevalent tick-borne illness in the northern hemisphere, affecting multiple body systems with low spirochaetaemia.
  • This study, conducted at the Mayo Clinic between 2003 and 2014, involved testing clinical specimens and identifying a novel Borrelia species through atypical PCR results and tick analysis.
  • The findings revealed six patients with atypical PCR profiles indicating a new genospecies, which was also found in local ticks, highlighting potential new implications for Lyme disease diagnosis and treatment in the USA.
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