Progesterone therapy for prevention of recurrent spontaneous preterm birth in a minority patient population: a retrospective study.

Background: Preterm birth is a leading cause of infant morbidity and mortality worldwide. The burden of prematurity underscores the need for effective risk reduction strategies. The purpose of this study is to evaluate the efficacy of progesterone therapy, both intramuscular 17-α-hydroxyprogesterone caproate (IM 17-OHPC) and vaginal progesterone, in the prevention of recurrent spontaneous preterm birth (sPTB).

Atypical eclampsia in a normotensive patient with altered mental status and severely elevated transaminases: Case report and review.

Classically, pre-eclampsia and eclampsia are considered hypertensive disorders of pregnancy, and current diagnostic criteria include hypertension with proteinuria or other laboratory abnormalities or symptoms suggestive of end-organ damage. However, atypical presentations can occur in the absence of elevated blood pressures. We present the case of a pregnant patient who developed status epilepticus at 24 weeks and 4 days of gestation, followed by altered mental status and severely elevated transaminases.

Marijuana use and perinatal outcomes in obstetric patients at a safety net hospital.

Objective: To characterize the association between antepartum marijuana exposure and maternal and neonatal outcomes at our institution.

Study Design: Retrospective chart review identified an obstetric cohort of singleton gestations. Women with self-reported marijuana use were compared with non-users.

Amylase concentration and activity in the amniotic fluid of fetal rats with retinoic acid induced myelomeningocele.

Background: neurologic injury in myelomeningocele (MMC) occurs via a two-hit process: failed neural tube closure followed by neurodegeneration . Meconium in the amniotic fluid contains pancreatic digestive enzymes and is neurotoxic in rat models of MMC.

Objectives: The objectives of this study were to demonstrate the neurotoxicity of α-amylase and to compare the enzyme concentration and activity in the amniotic fluid of rats with retinoic acid induced MMC to a healthy control population.

Characteristics of referred patients with twin-twin transfusion syndrome who did not undergo fetal therapy.

Introduction: Abundant research has reported twin-twin transfusion syndrome (TTTS) outcomes following fetal therapy. Our research describes TTTS patients who did not undergo fetal therapy.

Methods: Records from TTTS pregnancies evaluated at 16 to 26 gestational weeks were reviewed between January 2006 and March 2017.

Graves' hyperthyroidism in pregnancy: a clinical review.

Background: Graves' hyperthyroidism affects 0.2% of pregnant women. Establishing the correct diagnosis and effectively managing Graves' hyperthyroidism in pregnancy remains a challenge for physicians.

Current trends in the diagnosis and management of gestational diabetes mellitus in the United States.

Objective: To assess current practice patterns among members of the Society for Maternal-Fetal Medicine (SMFM) with respect to the diagnosis and management of gestational diabetes mellitus (GDM).

Methods: A 38 question survey on GDM diagnosis and management was distributed to SMFM members.

Results: 2330 SMFM members were surveyed with a 40% response rate.

Home-based circuit resistance training to overcome barriers to exercise for people with spinal cord injury: a case study.

Background And Purpose: People with spinal cord injury (SCI) have limited options for aerobic exercise. Existing options are often difficult to access, or they result in muscle imbalances that can eventually contribute to joint dysfunction. These difficulties can cause individuals to live a more sedentary lifestyle, putting them at greater risk for developing obesity and other cardiovascular disease risk factors.