Publications by authors named "Elizabeth S Berge"
Adv Healthc Mater
January 2019
Article Synopsis
- Vascularization is crucial for overcoming diffusion limits in creating complex engineered tissues and organoids, which can be achieved through self-assembly of vascular networks using stem cell-derived endothelial cells and pericytes in hydrogels.*
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- Autofluorescence multiphoton microscopy (aMPM) is utilized as a label-free imaging method to quantitatively assess the morphology of these in vitro vascular networks without needing traditional fixation or labeling.*
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- Findings showed that bioreactors using recirculating or continuous fluid flow improve vascular network formation by reducing anisotropy and increasing branch points compared to static conditions, supporting the effectiveness of aMPM for optimizing tissue growth conditions.*
