Significance: An equivalent 12 months of cleaning did not induce significant changes in the optical aberrations or base curves of scleral lenses.
Purpose: This study aimed to test whether an equivalent of 12 months of manual cleaning alters the optical and physical properties of conventional and wavefront-guided scleral lenses.
Methods: Twelve scleral lenses (four repeats of three designs, termed A, B, and C) were manufactured in Boston XO material: design A, -5.