A dataset of proteins associated with mRNAs.

Post-transcriptional gene regulation in , the etiological agent of Chagas disease, plays a critical role in ensuring that the parasite successfully completes its life cycle in both of its obligate hosts: insect vector and mammals. This regulation is basically governed by RNA binding proteins (RBPs) through their interactions with -elements located in the UTRs of their mRNA targets. LYT1 gene, coding for a virulence factor of , is expressed into two isoforms: kLYT1 and mLYT1, which play different functions according to their cellular location and parasite life-cycle stages.

Molecular Characterization of Tc964, A Novel Antigenic Protein from .

The Tc964 protein was initially identified by its presence in the interactome associated with the LYT1 mRNAs, which code for a virulence factor of . Tc964 is annotated in the genome as a hypothetical protein. According to phylogenetic analysis, the protein is conserved in the different genera of the Trypanosomatidae family; however, recognizable orthologues were not identified in other groups of organisms.