Publications by authors named "Elizabeth Rondain"
A Southeast Asia Consensus on the Definition and Management of Treatment-Resistant Depression.
Neuropsychiatr Dis Treat
November 2022
Article Synopsis
- - The text discusses the lack of a universal definition for treatment-resistant depression (TRD) in Southeast Asia, demonstrating the need for a standardized approach to its management across the region.
- - A panel of 13 psychiatrists developed a new term, "pharmacotherapy-resistant depression" (PRD), defining it as the failure of two adequate drug treatments during a major depressive episode, and outlined a stepwise treatment plan including medication adjustments and non-pharmacological options.
- - The consensus recommendations can be adapted to different Southeast Asian contexts, but the importance of clinical judgment and individual patient circumstances in treatment decisions remains emphasized.
Objective: To evaluate the effect of 6 months of treatment with paliperidone extended-release (ER) tablets on the sleep profile of patients with schizophrenia.
Methods: A total of 984 patients meeting the (DSM-IV) criteria for schizophrenia who switched their antipsychotic to paliperidone ER were recruited from 61 sites in five countries in Southeast Asia. We recorded patient demographics and assessed sleep quality and daytime drowsiness using visual analog scales.