Riemann-Based Algorithms Assessment for Single- and Multiple-Trial P300 Classification in Non-Optimal Environments.

The P300 wave is commonly used in Brain-Computer Interface technology due to its higher bit rates when compared to other BCI paradigms. P300 classification pipelines based on Riemannian Geometry provide accuracies on par with state-of-the-art pipelines, without having the need for spatial filters, and also possess the ability to be calibrated with little data. In this study, five different P300 detection pipelines are compared, with three of them using Riemannian Geometry as either feature extraction or classification algorithms.

Design principles for robust oscillatory behavior.

Oscillatory responses are ubiquitous in regulatory networks of living organisms, a fact that has led to extensive efforts to study and replicate the circuits involved. However, to date, design principles that underlie the robustness of natural oscillators are not completely known. Here we study a three-component enzymatic network model in order to determine the topological requirements for robust oscillation.

Influence of parameter values on the oscillation sensitivities of two p53-Mdm2 models.

Biomolecular networks that present oscillatory behavior are ubiquitous in nature. While some design principles for robust oscillations have been identified, it is not well understood how these oscillations are affected when the kinetic parameters are constantly changing or are not precisely known, as often occurs in cellular environments. Many models of diverse complexity level, for systems such as circadian rhythms, cell cycle or the p53 network, have been proposed.