Publications by authors named "Elizabeth P Hudson"
The commonly used Chromsystems vitamin C (ascorbate) assay (Munich, Germany) has a sample storage life of five days at -20°C. Stabilizing agents have been successfully used to increase longevity; however, their suitability with this commercial assay is unclear. We investigated the compatibility of a stabilizing agent, perchloric acid/diethylenetriaminepentaacetic acid (PCA/DTPA), with the Chromsystems assay.
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- A study was conducted to investigate if a combination of vitamin C, hydrocortisone, and thiamine is more effective than just hydrocortisone for treating septic shock.
- The trial included 216 patients from various intensive care units in Australia, New Zealand, and Brazil, and lasted from May 2018 to October 2019.
- Results showed no significant difference in the duration of being alive and free from vasopressor administration between the two treatment groups, as well as no substantial differences in other secondary outcomes, including mortality rates.
Objectives: To study vitamin C pharmacokinetics in septic shock.
Design: Prospective pharmacokinetic study.
Setting: Two intensive care units.