Publications by authors named "Elizabeth Magrath"

Article Synopsis
  • Understanding in vivo brain biomechanics is crucial for studying traumatic brain injury (TBI) mechanisms and prevention.
  • Researchers used tagged magnetic resonance imaging to measure brain deformations in 34 healthy volunteers during mild head angular accelerations.
  • The study found that maximum shear strain was highest in cortical gray matter, with significant differences in strain across various brain regions, but no notable gender differences in head accelerations or strain were observed.
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The data presented in this article is related to the research article entitled "Longitudinal multiple sclerosis lesion segmentation: Resource and challenge" (Carass et al., 2017) [1]. In conjunction with the 2015 International Symposium on Biomedical Imaging, we organized a longitudinal multiple sclerosis (MS) lesion segmentation challenge providing training and test data to registered participants.

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In conjunction with the ISBI 2015 conference, we organized a longitudinal lesion segmentation challenge providing training and test data to registered participants. The training data consisted of five subjects with a mean of 4.4 time-points, and test data of fourteen subjects with a mean of 4.

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In vivo measurements of human brain deformation during mild acceleration are needed to help validate computational models of traumatic brain injury and to understand the factors that govern the mechanical response of the brain. Tagged magnetic resonance imaging is a powerful, noninvasive technique to track tissue motion in vivo which has been used to quantify brain deformation in live human subjects. However, these prior studies required from 72 to 144 head rotations to generate deformation data for a single image slice, precluding its use to investigate the entire brain in a single subject.

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