Publications by authors named "Elizabeth Ma Hensor"
Article Synopsis
- - The study aimed to assess whether cardiovascular disease (CVD) in patients with early rheumatoid arthritis (ERA) could be improved with disease-modifying antirheumatic drugs (DMARDs), comparing the combination of etanercept (ETN) and methotrexate (MTX) against an MTX-only strategy.
- - In the trial with 81 ERA patients, baseline measurements indicated significantly lower aortic distensibility and left ventricular mass, as well as increased myocardial extracellular volume compared to matched controls, with improvements in aortic distensibility observed over the first year.
- - Findings suggest that the use of DMARD therapy, while showing vascular and myocardial improvements in ERA patients, did not depend on the specific DMARD
Unlabelled: Interosseous tendon inflammation (ITI) has been described in rheumatoid arthritis (RA). Whether ITI occurs in at-risk individuals before the onset of clinical synovitis is unknown.
Objectives: To investigate, by MRI, ITI in anti-cyclic citrullinated peptide (CCP)-positive at-risk individuals (CCP +at risk) and to describe the anatomy, prevalence and clinical associations across the RA continuum.
Lack of reproducibility is an ongoing problem in some areas of the biomedical sciences. Poor experimental design and a failure to engage with experienced statisticians at key stages in the design and analysis of experiments are two factors that contribute to this problem. The RIPOSTE (Reducing IrreProducibility in labOratory STudiEs) framework has been developed to support early and regular discussions between scientists and statisticians in order to improve the design, conduct and analysis of laboratory studies and, therefore, to reduce irreproducibility.
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