Publications by authors named "Elizabeth M Everson"
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Synopsis of recent research by authors named "Elizabeth M Everson"
Elizabeth M Everson's research primarily focuses on the development and evaluation of foamy viral (FV) vectors for use in hematopoietic stem cell (HSC) gene therapy, emphasizing their safety and efficacy compared to traditional retroviral vectors.
Her studies demonstrate that FV vectors, especially those integrated with insulators, show a favorable integration profile and lower genotoxicity, making them potentially safer alternatives for clinical applications.
Everson's findings indicate that foamy vectors exhibit reduced clonal dominance in HSCs, improving the prospects for effective gene therapy while minimizing risks associated with vector-induced genotoxicity.