The Brain in Kidney Disease (BRINK) Cohort Study: Design and Baseline Cognitive Function.

Background: The Brain in Kidney Disease (BRINK) Study aims to identify mechanisms that contribute to increased risk for cognitive impairment in patients with chronic kidney disease (CKD). We describe the rationale, design, and methods of the study and report baseline recruitment and cognitive function results.

Study Design: Longitudinal observational cohort study of the epidemiology of cognitive impairment in CKD.