Publications by authors named "Elizabeth L Tenorio"

Article Synopsis
  • This study aimed to investigate the range of neurological complications associated with COVID-19 in the UK, as existing research was limited and mostly based on small samples.
  • An online network of UK neuroscience organizations was created to report and classify various neurological symptoms linked to COVID-19, such as cerebrovascular events and altered mental status, allowing for both prospective and retrospective case reporting.
  • The data collected will help to better understand how COVID-19 affects brain health, enabling more informed decisions on potential therapies and treatment strategies.
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Background: Bacteroides fragilis is a Gram-negative anaerobe that is normally a human gut commensal; it comprises a small percentage of the gut Bacteroides but is the most frequently isolated Bacteroides from human infections. Identification of the essential genes necessary for the survival of B. fragilis provides novel information which can be exploited for the treatment of bacterial infections.

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Background: Porphyromonas gingivalis is a Gram-negative anaerobic bacterium associated with periodontal disease onset and progression. Genetic tools for the manipulation of bacterial genomes allow for in-depth mechanistic studies of metabolism, physiology, interspecies and host-pathogen interactions. Analysis of the essential genes, protein-coding sequences necessary for survival of P.

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Background: Periodontitis is recognized as a complex polymicrobial disease, however, the impact of the bacterial interactions among the 700-1,000 different species of the oral microbiota remains poorly understood. We conducted an in vitro screen for oral bacteria that mitigate selected virulence phenotypes of the important periodontal pathogen, Porphyromonas gingivalis.

Method: We isolated and identified oral anaerobic bacteria from subgingival plaque of dental patients.

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