Publications by authors named "Elizabeth Kaiser"
Article Synopsis
- * Adults with TOF, whether repaired or unrepaired, often face complications such as heart failure and late arrhythmias, primarily due to right ventricular (RV) failure stemming from chronic pulmonary regurgitation.
- * Current treatments for RV failure related to TOF, including pulmonary-valve replacement and other surgical options, have not effectively reduced mortality or failure rates, signaling a need for new strategies and deeper understanding of the underlying mechanisms.
A lower baseline neutrophil-to-eosinophil ratio (NER) has been associated with improved responses to immune checkpoint inhibitors (ICI)-treated metastatic renal cell carcinoma (mRCC). This study investigated the decrease in NER at week 6 after ipilimumab/nivolumab (ipi/nivo) initiation and treatment responses in mRCC. A retrospective study of ipi/nivo-treated mRCC at two US academic cancer centers was conducted.
View Article and Find Full Text PDFMacrophages, which are abundant in the tumour microenvironment, enhance malignancy. At metastatic sites, a distinct population of metastasis-associated macrophages promotes the extravasation, seeding and persistent growth of tumour cells. Here we define the origin of these macrophages by showing that Gr1-positive inflammatory monocytes are preferentially recruited to pulmonary metastases but not to primary mammary tumours in mice.
View Article and Find Full Text PDFBackground: The Batista operation, or partial ventriculectomy, has been designed by the Brazilian surgeon Dr. Randas Batista as an alternative method for treating patients with idiopathic dilated cardiomyopathy.
Hypothesis: This study aimed to analyze electro- and vectorcardiographic data obtained from patients who underwent such surgery, and to evaluate its electrical repercussions on the heart.
Although the lung is the primary target of involvement, sarcoidosis can involve any organ in the body, including the eye. Ocular involvement may also be the initial manifestation of sarcoidosis in many patients. Since no characteristic clinical feature heralds the onset of ocular involvement in sarcoidosis, a systematic eye examination is advised.
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