Publications by authors named "Elizabeth J Trimble"

There may be inter-/intra-surgeon variability in the repair of congenital heart defects. The objective was to analyze and visualize inter-/intra-surgeon variability in the level of patch suture lines and in the shape and size of patches developed through surgical simulation for partial anomalous pulmonary venous connection (PAPVC) repair using a patient-specific 3D-printed heart model. A patient with PAPVC and preoperative computed tomography data were selected, and a patient-specific heart model was obtained.

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Pulmonary nodules are frequently encountered in high-risk patients. Often these require biopsy which can be challenging. We relate our experience comparing use of electromagnetic navigational bronchoscopy (ENB) to a robotic bronchoscopy system (RB).

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Objective: Hypoplastic left heart syndrome (HLHS) is a congenital disease characterized by an underdevelopment of the anatomical components inside the left heart. Approximately 30% of HLHS newborns will develop tricuspid regurgitation (TR), and it is currently unknown how the valve annulus mechanics and geometry are associated with regurgitation. Thus, we present an engineering mechanics-based analysis approach to quantify the mechanics and geometry of the HLHS-afflicted tricuspid valve (TV), using 4-dimensional echocardiograms.

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Article Synopsis
  • Blepharospasm (BSP) is a type of focal dystonia marked by uncontrolled spasms of the eyelid muscles and shows significant genetic influences, but research is limited by small study sizes and other challenges.
  • Researchers conducted whole-exome sequencing on 31 individuals from 21 families with BSP, confirming candidate genetic variants linked to the condition through advanced sequencing methods.
  • Several genetic variants were identified in multiple genes previously not associated with isolated BSP, highlighting the need for further research to better understand the genetic complexities and factors contributing to this disorder.
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