Recent development in the synthesis of imidazo[1,5-]indole derivatives: an in-depth overview.

In the realm of nitrogen-fused heterocycles, imidazo[1,5-]indole and its derivatives are recognized as privileged structural patterns in various pharmaceutical drugs and biologically active natural products, emphasizing their significance. This review comprehensively explores the synthetic strategies for constructing imidazo[1,5-]indole scaffolds, with a particular focus on transition metal-catalyzed methodologies. The primary highlighted method is [4 + 1] annulation, along with other notable approaches such as C-H activation/cyclization, enantioselective C-H annulation, intramolecular hydroamination, and double cyclization processes.

Current developments in the synthesis of 4-chromanone-derived compounds.

The chroman-4-one framework is a significant structural entity that belongs to the class of oxygen-containing heterocycles. It acts as a major building block in a large class of medicinal compounds, and synthetic compounds exhibit a broad variety of remarkable biological and pharmaceutical activities. Several studies have been performed to improve the methodologies of 4-chromanone-derived compounds.

Cyclodextrin based palladium catalysts for Suzuki reaction: An overview.

The Suzuki reaction is one of the most effective methods for the formation of carbon-carbon bonds and is of great utility in organic synthesis. Recently, cyclodextrin based palladium catalysts were found to be very selective, convenient and efficient for Suzuki cross-coupling reactions. This review focuses on such cyclodextrin systems of palladium which act as efficient catalysts with high catalytic activity and recyclability in Suzuki reaction and covers literature up to 2019.