Publications by authors named "Elizabeth I Andersen"
Article Synopsis
- The Proton-Coupled Folate Transporter (PCFT) is crucial for absorbing dietary folates in the small intestine and for taking up antifolate drugs used in cancer treatment.
- This study examined how different lipids in Lipid-Protein Nanodiscs (LPNs) can influence the expression and solubilization of PCFT in a lab setting.
- Results showed that certain lipids, specifically dimyristoyl phosphatidylglycerol (DMPG) and dimyristoyl phosphatidylcholine (DMPC), successfully supported soluble PCFT expression, providing valuable insights into PCFT's lipid preferences and aiding future research on folate transport mechanisms.
