Publications by authors named "Elizabeth Hurlburt"
is an evolving and concerning global threat. Of particular concern are bloodstream infections related to central venous catheters. We evaluated the activity of taurolidine, a broad-spectrum antimicrobial in catheter lock solutions, against 106 .
View Article and Find Full Text PDFArticle Synopsis
- Catheter-related bloodstream infections (CRBSIs) are common, serious complications in patients on hemodialysis using central venous catheters, prompting a study (LOCK IT-100) to evaluate a new taurolidine/heparin solution compared to standard heparin.
- The trial included 795 patients and found that those using the taurolidine/heparin solution had significantly fewer CRBSIs (2% vs. 8% in the heparin group), indicating a 71% reduced risk of infection with the new solution.
- The study concluded that the taurolidine/heparin solution was effective in preventing CRBSIs without compromising safety, with most side effects being mild or moderate.