Publications by authors named "Elizabeth Hilow"
Adv Exp Med Biol
August 2011
Article Synopsis
- - Thiazolidinediones (TZDs), such as pioglitazone, show potential neuroprotective effects in rat models of stroke through various administration routes.
- - In a study, rats received different doses of oral pioglitazone prior to a simulated stroke (MCAO), with the two higher doses (0.65 mg/kg and 0.40 mg/kg) significantly reducing brain damage and improving motor functions compared to the lowest dose (0.20 mg/kg), which had no significant effects.
- - The study included assessments of motor and sensory abilities post-stroke using various tests, revealing enhanced recovery in rats treated with the higher doses of pioglitazone.
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