Publications by authors named "Elizabeth D Amarh"
Article Synopsis
- Mycobacterium abscessus infections often occur in cystic fibrosis patients and are difficult to treat due to their resistance to antibiotics.
- Bacteriophage therapy shows promise but faces challenges, such as varying susceptibility among different strains and the need for personalized treatments.
- New research on M. abscessus isolates reveals unusual prophage patterns and limited phage infections, highlighting the need for better understanding to improve phage therapy for non-tuberculous mycobacterial infections.
Article Synopsis
- - Mycobacteriophage phiT45-1 is a newly discovered bacteriophage that comes from strain Taiwan-45 and can lyse (destroy) the bacteria strain BWH-C.
- - This phage can also infect another strain called ATCC 19977, but it does not work on certain other bacteria.
- - phiT45-1 has a genome size of 43,407 base pairs and contains a special toxin-immunity system linked with type VII secretion systems.
Mycobacteriophage phiT46-1 is a newly isolated phage that was isolated by spontaneous release from strain Taiwan-46 and infects strain BWH-C. Phage phiT46-1 is unrelated to previously described mycobacteriophages, has a 52,849-bp genome, and includes a polymorphic toxin-immunity cassette associated with type VII secretion systems.
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