Publications by authors named "Elizabeth Curto"
Article Synopsis
- The study aimed to evaluate the clinical outcomes of using blunt scissors dissection for treating calcific corneal degeneration in older dogs, under topical anesthesia, over a period from 2015 to 2021.
- A total of 65 eyes from 57 dogs were analyzed, with most cases healing within 14 days, although a 1-year recurrence rate was found to be 25%, and globe rupture occurred in 4.6% of cases during the procedure.
- The results suggest that this surgical method can be effective and less invasive than previous treatments, but it's crucial that it is performed by trained professionals with thorough client communication about potential risks.
Long-term success rate of entropion surgery is equivalent in juvenile and adult dogs.
J Am Vet Med Assoc
February 2024
Article Synopsis
- The study aimed to analyze the long-term effects of lower lid entropion surgery in juvenile versus adult dogs and assess the temporary tacking procedure for dogs under 1 year old.
- Involving 116 client-owned dogs, researchers looked at those under 3 years old with primary lower lid entropion from 2010 to 2020, noting success rates and recurrence post-surgery.
- Results indicated no significant difference in recurrence rates between juvenile and adult dogs after surgery, suggesting that surgery for juvenile dogs could be performed without delay for better outcomes.
OBJECTIVE To determine the effects of grape seed extract (GSE), lutein, and fish oil containing omega-3 fatty acids on oxidative stress, migration, proliferation, and viability of lens epithelial cells (LECs). SAMPLE Lens capsules or cultured LECs obtained from canine cadavers. PROCEDURES An antioxidant reductive capacity assay was used to determine reducing capability of each substance.
View Article and Find Full Text PDFOBJECTIVE To compare complications between healthy horses undergoing general anesthesia for ophthalmic versus non-ophthalmic procedures and identify potential risk factors for the development of complications. DESIGN Retrospective case series. ANIMALS 502 horses (556 anesthetic procedures).
View Article and Find Full Text PDFObjective: To determine whether horses with clinically diagnosed Equine Recurrent Uveitis (ERU) and those with Leptospirosis infection have a specific cytokine profile in their aqueous humor (AH) and serum that differs from horses with uveitis secondary to other ocular inflammatory processes and from horses with normal eyes.
Animals Studied: Twenty-five client-owned horses with uveitis that were presented to the North Carolina State University Ophthalmology Service, and four University-owned horses without history or clinical signs of ocular disease.
Procedure: Samples of AH and serum were obtained from horses with ERU (n=13), acute or non-recurrent uveitis (UV; n=7), uveitis secondary to infectious keratitis (IK; n=5), and normal eyes (N; n=4).
A 1-year-old male castrated Pug was referred for unilateral exophthalmos unresponsive to oral antibiotic and anti-inflammatory therapy. Clinical findings included exophthalmos of the left eye with lateral strabismus, resistance to retropulsion, and an elevated nictitans. Hematologic and biochemical analyses were within normal limits.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to find the effective dose and delivery time of Cyclosporine A (CsA) needed to prevent posterior capsule opacification (PCO) in an ex vivo canine model while exploring how CsA induces cell death.
- Canine lens epithelial cells (LEC) treated with CsA showed reduced viability and specific morphological changes, and further analysis indicated that CsA leads to cell death primarily through autophagy rather than significant apoptosis.
- Treatment with CsA for 6 days at a concentration of 10 μg/mL effectively prevented the formation of PCO in cultured lens capsules, highlighting the potential therapeutic role of CsA in lens surgery outcomes.
Article Synopsis
- - The study aimed to assess how an aloe vera solution affects corneal cell viability, wound healing, and the activity of specific enzymes related to collagen degradation.
- - While aloe did not significantly impact cell viability, lower concentrations showed potential to slightly improve wound healing in corneal epithelial cells, whereas higher concentrations slowed fibroblast healing.
- - The aloe solution increased collagenase activity on Type IV collagen but did not affect its degradation of gelatin or Type I collagen, indicating the need for further research before moving to live animal studies.
Purpose: To characterize and describe the histopathologic findings in equine globes enucleated due to glaucoma.
Methods: Medical records at The Ohio State University from 1999 to 2012 were reviewed retrospectively. Signalment, history, and treatment data were collected, and histologic slides of enucleated globes were examined and lesions recorded.