Safety of rapid injection of undiluted ferric carboxymaltose to patients with iron-deficiency anaemia: a Phase II single-arm study.

Background: Ferric carboxymaltose is increasingly utilised to treat iron deficiency and is usually diluted in saline and administered as an intravenous infusion over 15 min. Although this is highly convenient compared with older formulations, we hypothesised the drug could be administered, safely given as a rapid bolus injection.

Aims: To define the risk of serious adverse events following administration of an undiluted, rapid, high-dose ferric carboxymaltose injection.

Community-associated methicillin-resistant Staphylococcus aureus in hospital nursery and maternity units.

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has rarely been reported in the hospital setting. We report an outbreak of 7 cases of skin and soft tissue infections due to a strain of CA-MRSA. All patients were admitted to the labor and delivery, nursery, or maternity units during a 3-week period.

Assessment and management of pediatric constipation in primary care.

Assessment and management of pediatric constipation is a challenging problem frequently faced by primary care practitioners. The purpose of this article is to offer a review of the literature including the definition of pediatric constipation and the presentation, etiology, and management of this common childhood disorder. Education and anticipatory guidance with children and their families should be included in the treatment regimen to prevent recurrences and promote health maintenance.