Sensitization to aeroallergens and airway hyperresponsiveness at 7 years of age.

Study Objectives: To investigate the relationship between current and early life factors and airway responsiveness to inhaled methacholine in children with a median age of 7.0 years.

Participants: Study subjects were a subset of a prospective birth cohort of children in the Boston area at high risk for atopy.

Clinical efficacy of microencapsulated timothy grass pollen extract in grass-allergic individuals.

Background: Conventional allergen immunotherapy is clinically effective in reducing the symptoms of allergic rhinitis and asthma. It differs from other pharmacotherapies in that it can induce long-term clinical remission of these diseases. However, it requires years of treatment and is associated with serious allergic reactions.