Optical Coherence Tomography in Knobloch Syndrome.

Background And Objective: Knobloch syndrome is a genetic disorder defined by occipital defect, high myopia, and vitreoretinal degeneration. The authors studied retinal changes in patients with Knobloch syndrome using optical coherence tomography (OCT).

Patients And Methods: The authors report patients with Knobloch syndrome who received OCT testing during their care from 2011 to 2016.

Spectral-domain optical coherence tomography findings in Alström syndrome.

Background: Alström syndrome is a multi-system recessive disorder caused by mutations in ALMS1 gene. The aim of this study was to characterize morphological retinal changes in Alström patients using spectral-domain optical coherence tomography.

Methods: We studied volunteer patients attending the conference of Alström Syndrome International, a support group for affected families, using hand-held spectral-domain optical coherence tomography (SD-OCT) in an office setting.

Segmental Analysis of Macular Layers in Patients With Unilateral Primary Open-Angle Glaucoma.

Purpose: To measure the thicknesses of the inner layers of the macula in both eyes of patients with unilateral primary open-angle glaucoma (POAG) and compare them with normal control eyes.

Methods: This prospective, cross-sectional pilot study enrolled patients with unilateral POAG, who had visual field defect in only 1 eye, and controls with a normal eye examination. Horizontal and vertical B-scan images centered on the fovea were obtained using spectral domain optical coherence.

Optical coherence tomography in optic nerve head avulsion.

Early diagnosis of optic nerve head (ONH) avulsion may be difficult due to an obscured fundus view. Although B-scan ultrasonography is more useful than MRI and CT imaging, it has limited sensitivity and specificity. Optical coherence tomography (OCT) can be used to identify optic nerve pathology.

Imaging modalities for localization of an iStent(®).

The iStent (Glaukos Corporation, Laguna Hills, CA) is a 1-mm, titanium trabecular bypass stent implanted across the inner wall of Schlemm's canal under direct gonioscopy. This study was designed to determine the best modality to identify iStent placement when gonioscopic visualization is not possible. In this in vitro study on a human cadaver eye, ultrasound biomicroscopy (UBM), anterior segment optical coherence tomography (AS-OCT), and B-scan ultrasonography were done to visualize and precisely locate two intentionally misplaced iStents.

High prevalence of plateau iris configuration in family members of patients with plateau iris syndrome.

Purpose: The purpose of the study was to ascertain the prevalence of plateau iris syndrome in the first-degree relatives of those patients affected with plateau iris syndrome.

Methods: All patients seen with plateau iris syndrome over a 5-year period were identified. These patients were approached for participation and first-degree family members above 18 years of age were screened.

Voluntary suppression of the multifocal electroretinogram.

Objective: To describe multifocal electroretinogram (mfERG) responses in 2 patients with nonorganic visual loss and in 11 eyes of 6 healthy persons who suppressed their mfERG responses.

Design: Observational case series.

Methods: The mfERG results were recorded in all individuals using the Veris Science 4.