Publications by authors named "Elizabeth A Foker"
Article Synopsis
- The text discusses a new method for creating enantiomerically enriched tetrahydronaphthalen-1-ols, which are a specific kind of organic compound.
- The synthesis involves a two-step process: alkylation using hydrogen borrowing and asymmetric transfer hydrogenation with ammonium formate, achieving high yields and good selectivity.
- The resulting compounds can be further modified into complex molecules, showcasing their potential applications in various fields.
The 7-azabicyclo[4.3.1]decane ring system, common to a number of biologically active alkaloids, was accessed from tropone (via its η-diene complex with Fe(CO)) in a short sequence of steps: 1) nucleophilic amine addition and subsequent Boc-protection, 2) photochemical demetallation of the iron complex, and 3) an intramolecular Heck reaction.
View Article and Find Full Text PDF