Publications by authors named "Elizabeth A Di Valerio"

Article Synopsis
  • Long-term data on calcium stone formers is scarce, but this study emphasizes the protective role of medical therapy (MT) in reducing future stone formation in high-risk patients over time.
  • The study tracked patients with calcium-oxalate and calcium-phosphate stones for 10 to 12 years, focusing on those who received MT, which includes medications like thiazides and potassium citrate.
  • Results showed that those on MT experienced fewer stone occurrences (21.3%) compared to those not on treatment (37.5%) over a mean follow-up of 10.6 years, with a notable difference in events based on stone subtype.
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Article Synopsis
  • - The study evaluates the diagnostic accuracy of the Vesical Imaging-Reporting and Data System (VI-RADS) in differentiating T1 from T2 bladder cancer, using various medical databases to gather relevant research.
  • - Six studies involving 624 MRI reports showed that a VI-RADS score of ≥3 had high sensitivity (93%) but lower specificity (61%) for detecting muscle invasion compared to T1 lesions.
  • - The findings suggest that a VI-RADS score of ≥3 is a reliable non-invasive tool for identifying T2 urothelial lesions, which could aid in improving bladder cancer diagnosis.
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Article Synopsis
  • A systematic review and meta-analysis was conducted to evaluate how consistently different readers interpret the VI-RADS scoring system for detecting muscle-invasive bladder cancer (MIBC) before surgery.
  • The analysis included 19 studies with 2439 participants, revealing that the level of agreement among readers was high, with a pooled inter-reader reliability score of 0.76.
  • Various factors, such as magnetic strength and the number of readers, contributed to differences in study results, but overall, the findings support the VI-RADS system's use in clinical practice for bladder cancer staging.
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Background: COVID-19 has heterogeneous manifestations, though one of the most common symptoms is a sudden loss of smell (anosmia or hyposmia). We investigated whether olfactory loss is a reliable predictor of COVID-19.

Methods: This preregistered, cross-sectional study used a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory illness.

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