Publications by authors named "Eliza Rajkowska"
Article Synopsis
- mRNA-based drugs are rapidly advancing, particularly as viral vaccines, with potential uses in various diseases due to their easy and adaptable production process.
- The structure of mRNA components, especially modifications at the 5' cap, significantly influences its effectiveness and longevity in medical applications.
- This study focuses on synthesizing modified cap analogues and testing these compounds for their ability to act as translation inhibitors and improve mRNA preparation.
Sixteen new Ciprofloxacin derivatives were designed and successfully synthesized. In an in silico experiment, lipophilicity was established for obtained compounds. All compounds were screened for antimicrobial activity using standard and clinical strains.
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