Publications by authors named "Eliza R Gentzler"
Article Synopsis
- This study investigates the real-world safety and effectiveness of selexipag in treating pediatric patients with pulmonary arterial hypertension (PAH).
- Researchers analyzed data from 87 children, tracking clinical outcomes before and after starting selexipag over various time periods.
- Results show that while add-on therapy improved some hemodynamic parameters early on, transition patients remained stable initially but faced potential functional decline later, indicating the need for continuous monitoring of these patients.
Article Synopsis
- The study investigates how levels of TRAIL, a protein that induces programmed cell death, are linked to outcomes like in-hospital mortality and organ dysfunction in sepsis patients.
- It was found that lower TRAIL levels correlate with increased organ dysfunction and higher incidence of septic shock across multiple patient groups.
- Additionally, lower TRAIL levels were inversely associated with RIPK3, a protein involved in another form of cell death called necroptosis, indicating a complex relationship between these pathways in critically ill patients.
Underdetection and Undertreatment of Dyspnea in Critically Ill Patients.
Am J Respir Crit Care Med
June 2019
Dyspnea is a common and distressing physical symptom among patients in the ICU and may be underdetected and undertreated. To determine the frequency of dyspnea relative to pain, the accuracy of nurses and personal caregiver dyspnea ratings relative to patient-reported dyspnea, and the relationship between nurse-detected dyspnea and treatment. This was an observational study of patients ( = 138) hospitalized in a medical ICU (MICU).
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