This article reports an update to the protocol of the IMASOY trial, which was prospectively registered on clinicaltrials.gov (NCT04110340) in October 2019.
Human mpox, caused by the human mpox virus (hMPXV), typically leads to fever and rash and has seen an unprecedented global outbreak since May 2022, prompting the MOSAIC study to assess clinical outcomes.
MOSAIC recruits participants of all ages with confirmed mpox, collecting various samples for PCR testing and clinical data over six months to understand the disease better.
The study quickly commenced within two months of the outbreak, focusing on effective research responses to emerging diseases, with final follow-ups expected in January 2024.