Path to a Profession: How a Physician Assistant Becomes a Physician Assistant.

This pilot study, through the application of phenomenological methodology, considered the physician assistant (PA) profession as a "lived experience" in an attempt to understand how these medical practitioners end up on the PA path and what keeps them there. Additionally, the researchers focused on understanding why specific individuals gravitate towards the PA education option. Major themes that developed during the interviews with eight PAs included personal unfamiliarity with the PA profession during the first two decades of life, the decision to pursue PA training while in undergraduate studies, assuming roles often considered MD/DO specific and the subsequent patient confusion with the difference between a PA and an MD/DO, and significant work satisfaction resulting in the lack of desire to change profession.

Embryo-larval BDE-47 exposure causes decreased pathogen resistance in adult male fathead minnows (Pimephales promelas).

Exposures to polybrominated diphenyl ethers (PBDEs) have been shown to alter immune function in adult organisms across a variety of taxa. However, few if any studies have investigated the long-term consequences of early life stage PBDE exposures on immune function in fish. This study sought to determine the effects of early life stage BDE-47 exposure on pathogen resistance in the fathead minnow (Pimephales promelas) following an extended depuration period (≥180 d).

Early Life Stage Exposure to BDE-47 Causes Adverse Effects on Reproductive Success and Sexual Differentiation in Fathead Minnows (Pimephales promelas).

2,2',4,4'-Tetrabromodiphenyl ether (BDE-47), a compound manufactured for use as a flame retardant, is a ubiquitous environmental contaminant and suspected endocrine disruptor. Though several studies have explored the reproductive effects of BDE-47 in adult fish, there is a paucity of data regarding the reproductive effects of early life stage exposure. The goal of this study was to assess the reproductive effects of early life stage BDE-47 exposure in fathead minnows (Pimephales promelas).

The endocrine effects of dietary brominated diphenyl ether-47 exposure, measured across multiple levels of biological organization, in breeding fathead minnows.

The goal of the present study was to evaluate the reproductive function of fathead minnows (Pimephales promelas) exposed to brominated diphenyl ether-47 (BDE-47) at doses lower than those used in previous studies. This was accomplished by evaluating the impacts of BDE-47 exposures across multiple levels of biological organization. Breeding pairs were exposed to BDE-47 via diet for 21 d, during which reproductive success was monitored.