Publications by authors named "Elisavet Kontou"
Article Synopsis
- Sleep disruption may impact immune response post-COVID-19 vaccination, particularly regarding antibody levels.
- The study involved 592 healthcare workers in Greece who received two doses of the Pfizer-BioNTech vaccine, with data collected on sleep habits and antibody measurements.
- Results indicated that insomnia, along with age and gender, independently influenced the levels of antibodies produced, highlighting the significance of good sleep for effective vaccination outcomes.
Anti-SARS-CoV-2 spike RBD (receptor-binding domain) IgG antibody levels were monitored in 1643 volunteer healthcare workers of Eginition, Evangelismos, and Konstantopoulio General Hospitals (Athens, Greece), who underwent vaccination with two doses of COVID-19 BNT162b2 mRNA vaccine (Pfizer) and had no history of SARS-CoV-2 infection. Venous blood was collected 20-30 days after the second vaccine dose and anti-RBD IgG levels were determined using CMIA SARS-CoV-2 IgG II Quant (Abbott) on ARCHITECT i System or ADVIA Centaur SARS-CoV-2 IgG (Siemens) on Centaur XP platform. From the total population of 1643 vaccinees (533 M/1110 F; median age = 49; interquartile range-IQR = 40-56), 1636 (99.
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