Publications by authors named "Elisavet Froukala"
Article Synopsis
- The study investigates the spread and evolution of carbapenemase-producing ST182 strains, which are increasingly linked to hospital infections worldwide.
- ST182 was found in patients across five continents from 2011 to 2021, and genetic analysis revealed diversity among these strains, with many carrying resistance and virulence genes.
- The research highlights ST182 as a concerning multidrug-resistant lineage that warrants careful monitoring due to its global presence and potential for further outbreaks.
Objectives: Streptococcus pyogenes causes superficial infections but can also cause deep-seated infections and toxin-mediated diseases. In the present study, phylogenetic and in silico prediction analyses were performed on an antimicrobial resistant M1S. pyogenes strain causing severe clinical manifestations during the current surge of invasive group A Streptococcus (iGAS) disease.
View Article and Find Full Text PDFNosocomial outbreaks of multidrug-resistant (MDR) complex (ECC) are often reported worldwide, mostly associated with a small number of multilocus-sequence types of and strains. In Europe, the largest clonal outbreak of -producing ECC has been recently reported, involving an ST182 strain in a Greek teaching hospital. In the current study, we aimed to further investigate the genetic make-up of two representative outbreak isolates.
View Article and Find Full Text PDFSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus responsible for the coronavirus disease 2019 (COVID-19) pandemic. Chains of infections starting from various countries worldwide seeded the outbreak of COVID-19 in Athens, capital city of Greece. A full-genome analysis of isolates from Athens' hospitals and other healthcare providers revealed the variety of SARS-CoV-2 that initiated the pandemic before lockdown and passenger flight restrictions.
View Article and Find Full Text PDFArticle Synopsis
- - The study analyzed 1,122 SARS-CoV-2-infected patients to examine the link between upper respiratory tract (URT) viral loads, host factors, and disease severity.
- - Results showed that patients with high viral loads were generally older, had more comorbidities, experienced more severe symptoms, and had longer ICU stays and intubation times compared to those with moderate or low viral loads.
- - The findings suggest that measuring URT viral load can help identify patients at greater risk for severe outcomes from COVID-19.
There is limited information on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection clustering within families with children. We aimed to study the transmission dynamics of SARS-CoV-2 within families with children in Greece. We studied 23 family clusters of coronavirus disease 2019 (COVID-19).
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