Publications by authors named "Elisavet Anna Chrysochoou"
Background: The utility of the forced oscillations technique (FOT) in cystic fibrosis (CF) remains uncertain. The aim of this study was to explore the ability of lower-frequency FOT indices, alone and after adjustment for the lung volume, to assess the extent of ventilation inhomogeneity in CF patients with varying disease severity.
Methods: Forty-five children, adolescents, and adults with CF (age 6.
Article Synopsis
- The study examined the impact of Elexacator/tezacaftor/ivacaftor (ETI) on the management of cystic fibrosis (CF) in 71 adult patients over one year.
- Results showed a significant decrease in the use of inhaled medications like dornase-α and several antibiotics after starting ETI, indicating improved health outcomes.
- The authors suggest that while these findings are promising, further research through larger clinical trials is necessary to fully understand the long-term effects of ETI on CF treatment.
Background: Adherence to pulmonary medication is pivotal in delaying the progression of lung disease in cystic fibrosis (CF). Further exploring the consequences of poor adherence and its impact on disease severity may be valuable to personalize CF treatment strategy.
Aim: To evaluate indicators of disease severity among children and adults with CF and investigate which of them are related to pulmonary medication adherence.
As Cystic Fibrosis (CF) treatment advances, research evidence has highlighted the value and applicability of Lung Clearance Index and Cardiopulmonary Exercise Testing as endpoints for clinical trials. In the context of these new endpoints for CF trials, we have explored the use of these two test outcomes for routine CF care. In this review we have presented the use of these methods in assessing disease severity, disease progression, and the efficacy of new interventions with considerations for future research.
View Article and Find Full Text PDFAcute clavicle osteomyelitis in children is rare representing <3% of osteomyelitis cases. We treated a 12-year-old boy who presented with acute pain in the right clavicle and high fever for 4 days. MRI showed abnormal signal in the right clavicle with periosteal reaction.
View Article and Find Full Text PDFBackground: The Paediatric Allergic Rhinitis Quality of Life Questionnaire (Ped-AR-QoL) is the first tool developed for the assessment of health-related quality of life (QoL) in Greek children with allergic rhinitis (AR).
Objective: The aim of the current study was to validate the child and parent forms of the Ped-AR-QoL in children aged 6-14 years-old who suffered from AR and were followed in a pediatric allergy clinic.
Methods: The Ped-AR-QoL, which was completed by 112 children and their parents, was correlated to the generic QoL questionnaire (Disabkids), which is already valid in Greece for children with chronic disorders, as well as with expert opinions on the severity of disease.